We watched an old episode of "House" last night, which makes me a doctor, right? The patient had some kind of autoimmune inflammatory problem, so at one point they treated her with plasmapheresis, describing it as a way to filter out excessive ... I don't know, immuno-particle thingies in her blood. That made me wonder if anyone's using that for COVID cytokine storms.
A search for "COVID and plasmapheresis" mostly gets you stories about convalescent serum, which is finally getting going on a significant scale now that there are more recovered COVID patients worldwide.
href="https://www.pnas.org/content/117/23/12526">This article suggests that convalescent serum might work even better if plasmapheresis were first used to strain out the excess immuno-stuff, so score one for the House screenwriters.
There was a wild, wild story in my local newspaper about the 24-year-old son of a woman I know slightly. Her son came down with COVID back in March, in a sudden and catastrophic form. He seems to have been in ordinarily robust health, just unlucky enough to suffer a vicious immune over-reaction. You can read about it
here if you want the gory details, but the short version is that in 3 months in an Austin hospital, where he seems to have received excellent care, he had just about everything done to him that can possibly be done to someone who ultimately survives: medically induced coma, heart-lung machine, dialysis, treatment for septic shock, treatment for a lung abscess, pneumothorax, and collapsed lung, 7 weeks of intubation, tracheostomy, and feeding tubes. One of the things they tried was convalescent serum, the first trial in that hospital. Whether that also included the "coffee filter" aspect of plasmapheresis isn't clear.
I'm also not sure whether they tried
dexamethasone, either (the article mentioned "experimental drug to try and treat the cytokine storm"), but that's getting some interest lately, too. We don't hate it yet, because the Bad Man hasn't recommended it.
The New York Times is already cautioning us that it may not be all it's cracked up to be in 100% of cases, so don't start getting optimistic about COVID, the economy, or society, because the important thing is DOOM.