Sen. Cruz says that states should simply defy the Supreme Court on gay marriage. I don't see how that could possibly work out well, as it didn't even work in cases (such as segregation) in which there was intense and unified opposition to the Supreme Court's ruling among the polities of many states. The American population has responded to years of all their favorite Hollywood entertainers endorsing this, combined with years of Federal court rulings all pointing in the same direction, by shifting its opinion to support for the practice. There are probably no states that can put together the unity against gay marriage that characterized the Southern Democrats' rejection of anti-segregation rulings.
On the other hand, segregation was immoral. If this set of arguments is even close to plausible, public opinion may well shift again in the coming years. In that case, the defiant will be remembered kindly by history rather than as the bigots they are portrayed as being in the contemporary press.
Much depends on what comes next. For the moment, Sen. Cruz is taking the lead boldly down a dark road. Whether that road ends in darkness, or whether joy comes with the morning, is far from clear.